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THE US Food and Drug Administration has rejected calls by the consumer group Public Citizen for a ban on Crestor, AstraZeneca’s cholesterol treatment, which the FDA has said is no more risky than other statins. Separately, AstraZeneca is promoting David Brennan, its head in North America, to the board, pushing him into the running for the CEO post.

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The METEOR trial examined AstraZeneca’s Crestor (rosuvastatin) in patients with early signs of atherosclerosis. C&I notes that because the METEOR study did not show regression of atherosclerosis, it ‘dashes hopes for an expanded label’ (C&I 2007, 7, 7). While METEOR did not show regression, this was not its primary endpoint.

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** CORONA (COntrolled ROsuvastatin multiNAtional Trial in Heart Failure) is
the first ever multi-national, prospective outcomes study to determine the
impact of statin treatment on heart
failure. The goal of the CORONA study is to determine the effect of
CRESTOR (rosuvastatin calcium) 10 mg on a combined endpoint of
cardiovascular death, non-fatal myocardial infarction, …

ASTRAZENECA has consolidated the advertising business for Crestor, moving professional advertising for the brand from WPP’s Grey Healthcare Group to Publicis’ Saatchi & Saatchi Healthcare Advertising following a competitive pitch.
The New York agency’s consumer advertising sibling, Saatchi & Saatchi Consumer Healthcare…

ASTRAZENECA is offering a 15-day free trial of cholesterol-lowering drug Crestor through a voucher campaign running in several national consumer publications. The effort follows similar “value” offers this year by other large pharmaceutical firms in an …

CHICAGO — A trial of AstraZeneca’s heart drug Crestor was stopped early because the drug proved so effective that the study’s independent monitors felt it would be unethical to withhold treatment from half the volunteers, company officials said Monday.

“We’re excited,” says Lisa Nanfra of AstraZeneca.

The decision…

A CONSUMER group has asked US regulators to ban AstraZeneca’s cholesterol lowering drug, Crestor, citing reports of dangerous reactions and one death. Public Citizen, the campaign group founded by the independent presidential candidate Ralph Nader, is a persistent critic o…

CHESHIRE, England, November 1 /PRNewswire/ — New data published today in the American Journal of Cardiology add to a growing body of data that CRESTOR(R) (rosuvastatin calcium) may improve kidney function. The study, Effect of Rosuvastatin on C-Reactive Protein and Renal Function in Patients with Chronic Kidney Disease, shows that CRESTOR 10 mg has favourable anti-inflammatory effects in patients with chronic kidney disease and is supportive of potential accompany…

LONDON (AFP) — Anglo-Swedish pharmaceuticals giant AstraZeneca said Wednesday it would sue seven generic drug manufacturers in the United States to defend its patent of cholesterol treatment Crestor.
The world’s top pharmaceutical…

AstraZeneca, Europe’s second-largest drugmaker, has presented a comprehensive, 30-page response to the US Food and Drug Administration urging the agency to remove Public Citizen’s Health Research Group’s petition to ban its cholesterol-lowering drug Crestor (ro…